Denovo peptide/protein sequencing

The sequence of peptide/protein is important to study the biological function of the peptide/protein. However, complete characterization of peptides/proteins, including post-translational modifications (PTMs), sequence mutations and variants, is very challenging. De novo sequencing is a process in which amino acid sequences are directly interpreted from tandem mass spectra without the assistance of a database.

Applications:

• Sequence analysis of protein/peptide, of which databases are unavailable

• PTMs analysis of protein/peptide, of which databases are unavailable

• Sequence analysis of CDR region or full-length of antibodies


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